Zinc Finger Protein 587 (ZNF587)

ZNF587 belongs to the krueppel C2H2-type zinc-finger protein family and contains 13 C2H2-type zinc fingers and 1 KRAB domain. ZNF587 may be involved in transcriptional regulation.Computer sequence analysis of human highly conserved zinc finger modules. A sub-family of zinc finger proteins by computer analyses and comparisons of five new finger domains against protein databases. This subclass of the cysteine-cysteine/histidine-histidine motif shows additional well conserved amino acid patterns and belongs to the human kox and gli-Kruppel gene family, sharing also the same stretches of regulatory zinc finger-containing proteins of mouse and Xenopus. ZF6 cDNA contains the most interesting sequence, encoding a putative multi-domain regulatory protein.