Immunoglobulin Kappa (Igk)

Immunoglobulin kappa constant, also known as IGKC, is a human gene that encodes a the constant domain of kappa-type light chains for antibodies. It is found on chromosome 2, in humans, within the Immunoglobulin kappa locus, IGK@.The EU sequence has the INV (3) allotypic marker, Ala-45 and Val-83. The ROY sequence has the INV (1,2) allotypic marker, Ala-45 and Leu-83.Immunoglobulin kappa locus, also known as IGK@, is a region on human chromosome 2 that contains genes for the kappa (κ) light chains of antibodies (or immunoglobulins).In humans the κ chain is coded for by V (variable), J (joining) and C (constant) genes in this region. These genes undergo V(D)J recombination to generate a diverse repertoire of immunoglobulins.