C-Type Natriuretic Peptide (CNP)

C-type natriuretic peptide (CNP) is a 22 amino acid peptide that has strong vasorelaxant properties. also known as NPPC,a protein encoded by the NPPC gene.Unlike atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP), CNP does not have direct natriuretic activity. This is because CNP is a selective agonist for the B-type natriuretic receptor (NPRB) whereas ANP and BNP are selective for NPRA.Natriuretic peptides comprise a family of 3 structurally related molecules: atrial natriuretic peptide (ANP), brain natriuretic peptide (BNP), and C-type natriuretic peptide, CNP, encoded by a gene symbolized NPPC. These peptides possess potent natriuretic, diuretic, and vasodilating activities and are implicated in body fluid homeostasis and blood pressure control.