Mitochondrial Ribosomal Protein L42 (MRPL42)

MRPL42 encodes a protein identified as belonging to both the 28S and the 39S subunits. Further experiments will be needed to identify the specific subunit localization. Sequence analysis identified three transcript variants that encode two different isoforms. Pseudogenes corresponding to this gene are found on chromosomes 4q, 6p, 6q, 7p, and 15q.The deduced human MRPL42 protein contains a 32-amino acid N-terminal mitochondrial import signal.The deduced 142-amino acid protein has a calculated molecular mass of 6.7 kD. They identified MRPL42 orthologs in mouse, Drosophila, and C. elegans, but not in yeast or E. coli. Mouse and human MRPL42 share 75.9% amino acid identity.